Structure via PubChem · Public domain (PubChem)
phorate
Sign in to saveAlso known as O,O-diethyl S-(ethylthio)methylphosphorodithioate, O,O-diethyl S-ethylthiomethylthiothionophosphate, O,O-diethyl S-[(ethylsulfanyl)methyl] dithiophosphate, O,O-diethyl S-(ethylthio)methyl phosphorodithioate, O,O-diethyl S-ethylmercaptomethyl dithiophosphate
Phorate is an organophosphate used as an insecticide and acaricide.
Chemical data
- Formula
- C7H17O2PS3
- Molecular weight
- 260.4 g/mol
- IUPAC name
- diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-lambda5-phosphane
- SMILES
- CCOP(=S)(OCC)SCSCC
- InChIKey
- BULVZWIRKLYCBC-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 101 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
368 papers- Case report: Treatment of severe phorate poisoning.Frontiers in toxicology · 2025
- Biodegradation of phorate by bacterial strains in the presence of humic acid and metal ions.Journal of basic microbiology · 2022
- Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes.Saudi journal of biological sciences · 2019
- Effect of Phorate on the Development of Hyperglycaemia in Mouse and Resistance Genes in Intestinal Microbiota.Antibiotics (Basel, Switzerland) · 2022
- Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature.Toxics · 2022
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 260.013
- Has use
- insecticide
Show 12 more facts
- time-weighted average exposure limit
- 0.05
- chemical formula
- C₇H₁₇O₂PS₃
- NIOSH Pocket Guide ID
- 0502
- density
- 1.16
- melting point
- -45
- vapor pressure
- 0.0008
- flash point
- 320
- solubility
- 0.005
- short-term exposure limit
- 0.2
- canonical SMILES
- CCOP(=S)(OCC)SCSCC
- subject has role
- acetylcholinesterase inhibitor
- Commons category
- Phorate
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Overview
- Toxicity
- References
- External links
Phorate is an organophosphate used as an insecticide and acaricide.
==Overview== At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammals including humans. It inhibits acetylcholinesterase and butyrylcholinesterase.
Excerpted from Wikipedia’s “phorate” article, available under the CC BY-SA 4.0 licence.