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phosphonate
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phosphonate

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Also known as phosphonates

thumb|right|General ester of phosphonic acid; in fact, the phosphorus has a formal charge of +1, the oxygen above it has a formal charge of −1, and the bond between them is single.

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Phosphonates
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25 sections
Contents
  • Basic properties
  • Synthesis
  • From phosphonic acid
  • Michaelis-Arbuzov reaction
  • From phosphorus trichloride
  • Reactions
  • Hydrolysis
  • Horner–Wadsworth–Emmons reaction
  • Structural sub-classes
  • Bisphosphonates
  • Thiophosphonates
  • Phosphonamidates
  • Occurrence in nature
  • Uses
  • Metal chelants
  • Concrete admixtures
  • Warheads in proteomics
  • Medicine
  • Niche uses
  • Toxicology
  • Biodegradation
  • Phosphonate compounds
  • See also
  • References
  • Further reading

thumb|right|General ester of phosphonic acid; in fact, the phosphorus has a formal charge of +1, the oxygen above it has a formal charge of −1, and the bond between them is single.

In organic chemistry, phosphonates or phosphonic acids are organophosphorus compounds containing groups, where R is an organic group (alkyl, aryl). If R is hydrogen then the compound is a dialkyl phosphite, which is a different functional group. Phosphonic acids, typically handled as salts, are generally nonvolatile solids that are poorly soluble in organic solvents, but soluble in water and common alcohols.

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