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picoline
EntityQ2092388· pop 14· linked from 29 articles

Also known as methylpyridine

Picoline refers to any of three isomers of methylpyridine (CH3C5H4N). They are all colorless liquids with a characteristic smell similar to that of pyridine. They are miscible with water and most organic solvents.

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  • Isomers
  • History
  • Environmental properties
  • References
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Picoline refers to any of three isomers of methylpyridine (CH3C5H4N). They are all colorless liquids with a characteristic smell similar to that of pyridine. They are miscible with water and most organic solvents.

== Isomers == {| class="sortable wikitable" |- ! Name(s) ! CAS# ! m.p. (°C) ! b.p. (°C) ! pKa of pyridinium ion ! structure |- | 2-Methylpyridine, α-picoline, 2-picoline | [109-06-8] | −66.7 | 129.4 | 5.96 | class=skin-invert-image|90px| |- | 3-Methylpyridine, β-picoline, 3-picoline | [108-99-6] | −18 | 141 | 5.63 |class=skin-invert-image|90px| |- | 4-Methylpyridine, γ-picoline, 4-picoline | [108-89-4] | 3.6 | 145.4 | 5.98 |class=skin-invert-image|48px| |- |} The CAS number of an unspecified picoline isomer is [1333-41-1]. The methyl group in 2- and 4- picolines is reactive; e.g., 2-picolines condenses with acetaldehyde in the presence of warm aqueous sodium hydroxide to form 2-propenylpyridine.

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