PIGT
Sign in to saveAlso known as MCAHS3, NDAP, PNH2, CGI-06, phosphatidylinositol glycan anchor biosynthesis class T
GPI transamidase component PIG-T is an enzyme that in humans is encoded by the PIGT gene.
Gene data
PIGT- Name
- phosphatidylinositol glycan anchor biosynthesis class T
- Type
- protein-coding
- Aliases
- CGI-06, MCAHS3, NDAP, PIG-T, PNH2
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
via MyGene.info
Gene · Ensembl
phosphatidylinositol glycan anchor biosynthesis class T
- Symbol
- PIGT
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:45,416,084-45,456,934
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6134
- exact match
- identifiers.org/ncbigene/51604
- genomic end
- 45456934
- genomic start
- 45416084
- cytogenetic location
- 20q13.12
via Wikidata · CC0
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Article
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GPI transamidase component PIG-T is an enzyme that in humans is encoded by the PIGT gene.
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.