Also known as Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.
The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017].
via MyGene.info
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Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.
==Function==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).