Structure via PubChem · Public domain (PubChem)
pinazepam
Sign in to savePinazepam (marketed under the brand name Domar and Duna) is a benzodiazepine drug. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.
Chemical data
- Formula
- C18H13ClN2O
- Molecular weight
- 308.8 g/mol
- IUPAC name
- 7-chloro-5-phenyl-1-prop-2-ynyl-3H-1,4-benzodiazepin-2-one
- SMILES
- C#CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
- InChIKey
- MFZOSKPPVCIFMT-UHFFFAOYSA-N
- XLogP
- 3.1
- Polar surface area
- 32.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- anxiety
via ChEMBL · EBI
Research
39 papers- Pinazepam: a precursor of N-desmethyldiazepam.European journal of clinical pharmacology · 1982
- Pinazepam: review of pharmacological properties and therapeutic efficacy.Clinical therapeutics · 1984
- Placental transfer and distribution of pinazepam and its metabolite N-desmethyldiazepam in the maternal and fetal rabbit: effect of the stage of gestation.European journal of drug metabolism and pharmacokinetics · 1989
- Placental transfer of pinazepam and its metabolite N-desmethyldiazepam in women at term.European journal of clinical pharmacology · 1984
- Metabolism of pinazepam by rat liver microsomes.European journal of drug metabolism and pharmacokinetics · 1981
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 308.072
Show 5 more facts
- Commons category
- Pinazepam
- chemical formula
- C₁₈H₁₃ClN₂O
- canonical SMILES
- C#CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
- subject has role
- anxiolytic
- MCN code
- 2933.91.71
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Pinazepam (marketed under the brand name Domar and Duna) is a benzodiazepine drug. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.
Pinazepam and its metabolite N-desmethyldiazepam are transferred to the developing fetus in utero, but the plasma drug level in the mother is usually significantly higher than in the fetus.
Excerpted from Wikipedia’s “pinazepam” article, available under the CC BY-SA 4.0 licence.