PKIG

Also known as PKI-gamma, protein kinase (cAMP-dependent, catalytic) inhibitor gamma, cAMP-dependent protein kinase inhibitor gamma

cAMP-dependent protein kinase inhibitor gamma is a protein that in humans is encoded by the PKIG gene.

Gene data

PKIG

Name: cAMP-dependent protein kinase inhibitor gamma
Type: protein-coding
Position: 44,531,762–44,624,247 (+)
Aliases: PKI-gamma
Ensembl: ENSG00000168734
RefSeq RNA: NM_001281444.2, NM_001281445.2, NM_007066.5, NM_181804.3, NM_181805.3
RefSeq protein: NP_001268373.1, NP_001268374.1, NP_008997.1, NP_861520.1, NP_861521.1

This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

Gene Ontology

Molecular function

cAMP-dependent protein kinase inhibitor activity cAMP-dependent protein kinase inhibitor activity

Article

2 sections

Contents

References
Further reading

cAMP-dependent protein kinase inhibitor gamma is a protein that in humans is encoded by the PKIG gene.

The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive PKA inhibitor, and is a predominant form of PKA inhibitors in various tissues. Three alternatively spliced transcript variants encoding the same protein have been reported.