PLAG1

Also known as PSA, SGPA, ZNF912, PLAG1 zinc finger, SRS4

Zinc finger protein PLAG1 is a protein that in humans is encoded by the PLAG1 gene.

Gene data

PLAG1

Name: PLAG1 zinc finger
Type: protein-coding
Position: 56,160,909–56,211,333 (−)
Aliases: PSA, SGPA, SRS4, ZNF912
Ensembl: ENSG00000181690
RefSeq RNA: NM_001114634.2, NM_001114635.2, NM_002655.3, XM_017013576.2, XM_047421866.1
RefSeq protein: NP_001108106.1, NP_001108107.1, NP_002646.2, XP_016869065.1, XP_047277822.1

Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].