poloxamer
Sign in to savethumb|General structurewith a = 2–130 and b = 15–67
In the Vinony graph
Vinony's link graph records 23 inbound references to poloxamer, and connects out to micelles, polyethylene glycol and digital object identifier.
It sits within the topics Non-ionic surfactants and Polymers.
Vinony links it to 9 Wikipedia language editions.
Research
6,711 papers- A review of poloxamer 407 pharmaceutical and pharmacological characteristics.Pharmaceutical research · 2006
- Poloxamer 188 as surfactant in biological formulations - An alternative for polysorbate 20/80?International journal of pharmaceutics · 2022
- Poloxamer: A versatile tri-block copolymer for biomedical applications.Acta biomaterialia · 2020
- Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications.Drug discovery today · 2019
- Purified poloxamer 188 for sickle cell vaso-occlusive crisis.The Annals of pharmacotherapy · 2004
via PubMed
Wikidata facts
- Subclass of
- chemical substance
Show 2 more facts
- subject has role
- excipient
- Commons category
- Poloxamers
Sources (2)
via Wikidata · CC0
~11 min read
Encyclopedic overview
10 sectionsContents
- Common poloxamer properties
- Micellization and phase transitions
- Uses
- Biological effect
- On multi drug resistant cancer cells
- On nuclear factor kappa B
- Potential degradation by sonication
- References
- Further reading
- External links
thumb|General structurewith a = 2–130 and b = 15–67
Poloxamers are nonionic triblock copolymers composed of a central hydrophobic chain of polyoxypropylene (poly(propylene oxide)) flanked by two hydrophilic chains of polyoxyethylene (poly(ethylene oxide)). The word was coined by BASF inventor, Irving Schmolka, who received the patent for these materials in 1973. Poloxamers are also known by the trade names Pluronic, Kolliphor (pharma grade), and Synperonic.
Excerpted from Wikipedia’s “poloxamer” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
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