POLR2F
Sign in to saveAlso known as HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15, polymerase (RNA) II subunit F
gene umano
Gene data
POLR2F- Name
- RNA polymerase II, I and III subunit F
- Type
- protein-coding
- Position
- 37,952,607–38,041,932 (+)
- Aliases
- HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15
- Ensembl
- ENSG00000100142
- RefSeq RNA
- NM_001301129.2, NM_001301130.2, NM_001301131.2, NM_001363825.1, NM_021974.5
- RefSeq protein
- NP_001288058.1, NP_001288059.1, NP_001288060.1, NP_001350754.1, NP_068809.1
This gene encodes the sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit, in combination with at least two other subunits, forms a structure that stabilizes the transcribing polymerase on the DNA template. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Gene Ontology
Biological process
DNA-templated transcriptiontranscription by RNA polymerase Itranscription initiation at RNA polymerase I promotertranscription elongation by RNA polymerase Itermination of RNA polymerase I transcriptiontranscription by RNA polymerase IItranscription by RNA polymerase IItranscription initiation at RNA polymerase II promoter
Molecular function
Pathways
RNA polymerase - Homo sapiens (human)Cytosolic DNA-sensing pathway - Homo sapiens (human)Huntington disease - Homo sapiens (human)Formation of RNA Pol II elongation complex Formation of the Early Elongation ComplexSignaling by FGFR in diseaseDevelopmental BiologyAdaptive Immune SystemTelomere MaintenanceSignal Transduction
via MyGene.info
Gene · Ensembl
RNA polymerase II, I and III subunit F
- Symbol
- POLR2F
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:37,952,607-38,041,932
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein POLR2F PDB 1qkl.png
Show 8 more facts
- HomoloGene ID
- 7178
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5435
- genomic end
- 38437922
- genomic start
- 38348614
- chromosome
- human chromosome 22
- cytogenetic location
- 22q13.1
- expressed in
- ganglionic eminence
Sources (4)
via Wikidata · CC0