POLR2G
Sign in to saveAlso known as RPB19, RPB7, hRPB19, hsRPB7, polymerase (RNA) II subunit G, RNA polymerase II subunit G
DNA-directed RNA polymerase II subunit RPB7 is an enzyme that in humans is encoded by the POLR2G gene.
Gene data
POLR2G- Name
- RNA polymerase II subunit G
- Type
- protein-coding
- Position
- 62,761,554–62,766,715 (+)
- Aliases
- RPB19, RPB7, hRPB19, hsRPB7
- Ensembl
- ENSG00000168002
- RefSeq RNA
- NM_002696.3
- RefSeq protein
- NP_002687.1
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq, Jan 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RNA polymerase II subunit G
- Symbol
- POLR2G
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:62,761,453-62,766,715
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein POLR2G PDB 2c35.png
Show 5 more facts
- HomoloGene ID
- 2019
- exact match
- identifiers.org/ncbigene/5436
- genomic end
- 62534182
- genomic start
- 62761565
- cytogenetic location
- 11q12.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
DNA-directed RNA polymerase II subunit RPB7 is an enzyme that in humans is encoded by the POLR2G gene.
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, the association of this subunit with the polymerase under suboptimal growth conditions indicates it may play a role in regulating polymerase function.