POLR2G

Also known as RPB19, RPB7, hRPB19, hsRPB7, polymerase (RNA) II subunit G, RNA polymerase II subunit G

DNA-directed RNA polymerase II subunit RPB7 is an enzyme that in humans is encoded by the POLR2G gene.

Gene data

POLR2G

Name: RNA polymerase II subunit G
Type: protein-coding
Position: 62,761,453–62,766,715 (+)
Aliases: RPB19, RPB7, hRPB19, hsRPB7
Ensembl: ENSG00000168002
RefSeq RNA: NM_002696.3
RefSeq protein: NP_002687.1

This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq, Jan 2009].

Gene Ontology

Biological process

DNA-templated transcription DNA-templated transcription initiation transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription initiation at RNA polymerase II promoter transcription elongation by RNA polymerase II

Molecular function

nucleic acid binding protein binding

Cellular component

nucleus nucleus nucleoplasm nucleoplasm RNA polymerase II, core complex RNA polymerase II, core complex RNA polymerase II, core complex nuclear DNA-directed RNA polymerase complex

Pathways

RNA polymerase - Homo sapiens (human)Huntington disease - Homo sapiens (human)Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Signaling by FGFR in disease Developmental Biology Adaptive Immune System Telomere Maintenance Signal Transduction HIV Life Cycle

via MyGene.info

Gene · Ensembl

RNA polymerase II subunit G

Symbol: POLR2G
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:62,761,453-62,766,715
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

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Encyclopedic overview

3 sections

Contents

Interactions
References
Further reading

DNA-directed RNA polymerase II subunit RPB7 is an enzyme that in humans is encoded by the POLR2G gene.

This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, the association of this subunit with the polymerase under suboptimal growth conditions indicates it may play a role in regulating polymerase function.

Excerpted from Wikipedia’s “POLR2G” article, available under the CC BY-SA 4.0 licence.