polymicrogyria
Sign in to saveAlso known as PMG
Polymicrogyria (PMG) is a condition that affects the development of the human brain by multiple small gyri (microgyri) creating excessive folding of the brain leading to an abnormally thick cortex. This abnormality can affect either one region of the brain or multiple regions.
Research
1,473 papers- ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.Brain : a journal of neurology · 2021
- Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria.JAMA neurology · 2023
- Polymicrogyria Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY.1993
- Polymicrogyria: pathology, fetal origins and mechanisms.Acta neuropathologica communications · 2014
- [Polymicrogyria].No to shinkei = Brain and nerve · 1999
via PubMed
Wikidata facts
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- NCI Thesaurus ID
- C116936
- exact match
- purl.obolibrary.org/obo/HP_0002126
- Commons category
- Polymicrogyria
Sources (3)
via Wikidata · CC0
~16 min read
Article
18 sectionsContents
- Syndromes
- Bilateral frontal polymicrogyria (BFP)
- Bilateral frontoparietal polymicrogyria (BFPP)
- Bilateral perisylvian polymicrogyria (BPP)
- Bilateral parasagittal parieto-occipital polymicrogyria (BPOP)
- Bilateral generalised polymicrogyria (BGP)
- Unilateral polymicrogyria
- Signs and symptoms
- Cause
- Pathology
- Diagnosis
- Neuroimaging techniques
- Neuropathological techniques
- Treatment
- Epidemiology
- History
- See also
- References
Polymicrogyria (PMG) is a condition that affects the development of the human brain by multiple small gyri (microgyri) creating excessive folding of the brain leading to an abnormally thick cortex. This abnormality can affect either one region of the brain or multiple regions.
The time of onset has yet to be identified; however, it has been found to occur before birth in either the earlier or later stages of brain development. Early stages include impaired proliferation and migration of neuroblasts, while later stages show disordered post-migration development.