hemimegalencephaly
Sign in to saveAlso known as unilateral megalencephaly, macrencephaly
Hemimegalencephaly (HME), or unilateral megalencephaly, is a rare congenital disorder affecting all or a part of a cerebral hemisphere. It causes severe seizures, which are often frequent and hard to control. A minority might have seizure control with medicines, but most will need removal or disconnection of the affected hemisphere as the best chance. Uncontrolled, they often cause progressive intellectual disability and brain damage and stop development.
In the Vinony graph
Within Vinony's link graph, hemimegalencephaly is referenced by 44 other articles, and connects out to congenital disorder, medication and International Standard Book Number.
It is catalogued under topics including Congenital disorders of nervous system, Neurological disorders and Rare diseases.
Its subject is documented across 6 Wikipedia language editions.
Research
657 papers- Hemimegalencephaly and tuberous sclerosis complex: A rare yet challenging association.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2021
- Hemimegalencephaly: A Systematic Comparison of Functional and Anatomic Hemispherectomy for Drug-Resistant Epilepsy.Neurosurgery · 2024
- Neuroimaging Findings in Fetal Hemimegalencephaly: Case Study and Review.Fetal diagnosis and therapy · 2024
- [Hemimegalencephaly].Ryoikibetsu shokogun shirizu · 2000
- [Hemimegalencephaly].Ryoikibetsu shokogun shirizu · 2002
via PubMed
Wikidata facts
Show 6 more facts
- ICD-9-CM
- 742.4
- health specialty
- rheumatology
- exact match
- www.orpha.net/ORDO/Orphanet_99802
- external data available at URL
- www.nanbyou.or.jp/entry/4783
- NCI Thesaurus ID
- C177779
- Commons category
- Hemimegalencephaly
via Wikidata · CC0
~3 min read
Encyclopedic overview
8 sectionsContents
- Symptoms and signs
- Other symptoms
- Genetics
- Pathophysiology
- Diagnosis
- Treatment
- References
- External links
Hemimegalencephaly (HME), or unilateral megalencephaly, is a rare congenital disorder affecting all or a part of a cerebral hemisphere. It causes severe seizures, which are often frequent and hard to control. A minority might have seizure control with medicines, but most will need removal or disconnection of the affected hemisphere as the best chance. Uncontrolled, they often cause progressive intellectual disability and brain damage and stop development.
==Symptoms and signs== Seizures are the main symptom. There can be as many as hundreds of seizures a day. Seizures tend to begin soon after birth, but may sometimes commence during later infancy or, rarely, during early childhood.
Excerpted from Wikipedia’s “hemimegalencephaly” article, available under the CC BY-SA 4.0 licence.