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Polyozellin
Sign in to savePolyozellin is a chemical which occurs in the mushroom Polyozellus multiplex. It inhibits prolyl endopeptidase, an enzyme that has a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease. Chemicals that inhibit prolyl endopeptidase have attracted research interest due to their potential therapeutic effects. Structurally related dibenzofuranyl derivatives of polyozellin are known as kynapcins.
In the Vinony graph
Vinony's link graph records 5 inbound references to Polyozellin, and connects out to enzyme, Alzheimer's disease and digital object identifier.
It is catalogued under topics including Acetate esters, Benzofuran ethers and Dibenzofurans.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C22H14O10
- Molecular weight
- 438.3 g/mol
- IUPAC name
- (12-acetyloxy-6,7,16,17-tetrahydroxy-10,20-dioxapentacyclo[11.7.0.03,11.04,9.014,19]icosa-1,3(11),4,6,8,12,14,16,18-nonaen-2-yl) acetate
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 438.058697
Show 3 more facts
- canonical SMILES
- CC(=O)OC1=C2C(=C(C3=C1C4=CC(=C(C=C4O3)O)O)OC(=O)C)C5=CC(=C(C=C5O2)O)O
- chemical formula
- C₂₂H₁₄O₁₀
- found in taxon
- Polyozellus multiplex
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Polyozellin is a chemical which occurs in the mushroom Polyozellus multiplex. It inhibits prolyl endopeptidase, an enzyme that has a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease. Chemicals that inhibit prolyl endopeptidase have attracted research interest due to their potential therapeutic effects. Structurally related dibenzofuranyl derivatives of polyozellin are known as kynapcins.
== References ==
Excerpted from Wikipedia’s “Polyozellin” article, available under the CC BY-SA 4.0 licence.