PPIB
Sign in to saveAlso known as CYP-S1, CYPB, HEL-S-39, OI9, SCYLP, peptidylprolyl isomerase B, B
gen van de soort Homo sapiens
In the Vinony graph
Within Vinony's link graph, PPIB is referenced by 10 other articles, and connects out to PubMed, Ensembl genome database project and prolyl isomerase.
It is catalogued under the topic Genes on human chromosome 15.
Its subject is documented across 4 Wikipedia language editions.
Gene data
PPIB- Name
- peptidylprolyl isomerase B
- Type
- protein-coding
- Position
- 64,155,740–64,163,159 (−)
- Aliases
- CYP-S1, CYPB, HEL-S-39, OI9, SCYLP
- Ensembl
- ENSG00000166794
- RefSeq RNA
- NM_000942.5
- RefSeq protein
- NP_000933.1
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
peptidylprolyl isomerase B
- Symbol
- PPIB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:64,155,740-64,163,159
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PPIB PDB 1cyn.png
Show 9 more facts
- HomoloGene ID
- 726
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5479
- genomic end
- 64163134
- genomic start
- 64155740
- chromosome
- human chromosome 15
- cytogenetic location
- 15q22.31
- expressed in
- pericardium
- Commons category
- Peptidyl-prolyl cis-trans isomerase B
Sources (3)
via Wikidata · CC0