PPP1R3C
Sign in to saveAlso known as PPP1R5, protein phosphatase 1 regulatory subunit 3C, PTG
Protein phosphatase 1 regulatory subunit 3C also known as PTG is an enzyme that in humans is encoded by the PPP1R3C gene.
Gene data
PPP1R3C- Name
- protein phosphatase 1 regulatory subunit 3C
- Type
- protein-coding
- Position
- 91,619,288–91,633,071 (−)
- Aliases
- PPP1R5, PTG
- Ensembl
- ENSG00000119938
- RefSeq RNA
- NM_005398.7
- RefSeq protein
- NP_005389.1
This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
protein phosphatase 1 regulatory subunit 3C
- Symbol
- PPP1R3C
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:91,619,288-91,633,071
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Protein phosphatase 1 regulatory subunit 3C also known as PTG is an enzyme that in humans is encoded by the PPP1R3C gene.
== Function ==
Excerpted from Wikipedia’s “PPP1R3C” article, available under the CC BY-SA 4.0 licence.