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propyl bromide

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propyl bromide

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Also known as n-propyl bromide, 1-bromopropane, bromopropane

1-Bromopropane (also known as '''n-propyl bromide or nPB''') is a bromoalkane with the chemical formula CH3CH2CH2Br. It is a colorless, flammable liquid that is used as a solvent. It has a characteristic hydrocarbon odor. Its industrial applications increased dramatically in the 21st century due to the phasing out of chlorofluorocarbons and chloroalkanes such as 1,1,1-trichloroethane under the Montreal Protocol. It was also used as a dry cleaning solvent as a substitute for perchloroethylene for a short time in the United States. 1-Bromopropane is highly neurotoxic to humans.

Chemical data

Formula
C3H7Br
Molecular weight
122.99 g/mol
IUPAC name
1-bromopropane
SMILES
CCCBr
InChIKey
CYNYIHKIEHGYOZ-UHFFFAOYSA-N
XLogP
2.1
Polar surface area
0 Ų
H-bond donors
0
H-bond acceptors
0
Formal charge
0

via PubChem

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Encyclopedic overview

9 sections
Contents
  • Preparation
  • Applications
  • Regulation
  • Safety
  • Animal studies
  • Environmental impact
  • Stratospheric ozone layer damage
  • References
  • Further reading

1-Bromopropane (also known as '''n-propyl bromide or nPB') is a bromoalkane with the chemical formula CH3CH2CH2Br. It is a colorless, flammable liquid that is used as a solvent. It has a characteristic hydrocarbon odor. Its industrial applications increased dramatically in the 21st century due to the phasing out of chlorofluorocarbons and chloroalkanes such as 1,1,1-trichloroethane under the Montreal Protocol. It was also used as a dry cleaning solvent as a substitute for perchloroethylene for a short time in the United States. 1-Bromopropane is highly neurotoxic to humans.

== Preparation == Industrial routes to 1-bromopropane involve free-radical additions to the corresponding alkenes. In this way, the anti-Markovnikov product is obtained. Alternatively, n''propanol may be substitutively brominated. The latter reaction is also viable laboratory synthesis.

Excerpted from Wikipedia’s “propyl bromide” article, available under the CC BY-SA 4.0 licence.