pseudohypoaldosteronism
Sign in to saveAlso known as Renal tubular acidosis, distal, type 4, Hyperkalemic distal renal tubular acidosis
Pseudohypoaldosteronism (PHA) is a condition that mimics hypoaldosteronism (presenting hyperkalemia). Two major types of primary pseudohypoaldosteronism are recognized and these have major differences in etiology and presentation.
In the Vinony graph
Within Vinony's link graph, pseudohypoaldosteronism is referenced by 225 other articles, and connects out to Online Mendelian Inheritance in Man, Conn's syndrome and cystinosis.
Vinony files it under Channelopathies, Nephrology and Pediatrics.
Its subject is documented across 10 Wikipedia language editions.
Key facts
- Medical condition (new).name
- Pseudohypoaldosteronism Type 1
- Medical condition (new).image
- Aldosterone-2D-skeletal.svg
- Medical condition (new).caption
- In pseudohypoaldosteronism type 1, aldosterone is elevated (hyperaldosteronism), but because the body fails to respond to it, it appears similar to hypoaldosteronism.
- Medical condition (new).symptoms
- Failure to thrive, dehydration, hyponatremia, metabolic acidosis, hyperkalemia, and other non-specific symptoms including nausea, vomiting, extreme fatigue, and muscle weakness.
- Medical condition (new).causes
- Mutations in the NR3C2, SCNN1A, SCNN1B, or SCNN1G genes
via Wikipedia infobox
Research
1,014 papers- Pseudohypoaldosteronism.Endocrine development · 2013
- Transient pseudohypoaldosteronism: a potentially severe condition affecting infants with urinary tract malformation.Journal of pediatric urology · 2019
- [Pseudohypoaldosteronism].Nihon rinsho. Japanese journal of clinical medicine · 1996
- Pseudohypoaldosteronism and mineralocorticoid receptor abnormalities.The Journal of steroid biochemistry and molecular biology · 1991
- Pulmonary manifestations of Pseudohypoaldosteronism type 1b: A systematic review of the literature.Paediatric respiratory reviews · 2025
via PubMed
Wikidata facts
Show 4 more facts
- NCI Thesaurus ID
- C85034
- exact match
- identifiers.org/doid/DOID:4479
- health specialty
- nephrology
- on focus list of Wikimedia project
- WikiProject Medicine
via Wikidata · CC0
~10 min read
Encyclopedic overview
20 sectionsContents
- Pseudohypoaldosteronism type 1 (PHA1)
- Mechanism
- Onset
- Symptoms
- Types
- Treatment
- Risks
- Pseudohypoaldosteronism type 2 (PHA2)
- Mechanism
- Onset
- Symptoms
- Types
- Treatment
- Risks
- Pregnancy risks
- Other risks
- History
- See also
- References
- External links
Pseudohypoaldosteronism (PHA) is a condition that mimics hypoaldosteronism (presenting hyperkalemia). Two major types of primary pseudohypoaldosteronism are recognized and these have major differences in etiology and presentation.
== Pseudohypoaldosteronism type 1 (PHA1) ==
Excerpted from Wikipedia’s “pseudohypoaldosteronism” article, available under the CC BY-SA 4.0 licence.