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pyrazolam

Structure via PubChem · Public domain (PubChem)

EntityQ15409343· pop 12· linked from 540 articles

Pyrazolam (SH-I-04) is a benzodiazepine derivative originally developed by a team led by Leo Sternbach at Hoffman-La Roche in the 1970s. It has since been "rediscovered" and sold as a designer drug since 2012.

Chemical data

Formula
C16H12BrN5
Molecular weight
354.2 g/mol
IUPAC name
8-bromo-1-methyl-6-pyridin-2-yl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
SMILES
CC1=NN=C2N1C3=C(C=C(C=C3)Br)C(=NC2)C4=CC=CC=N4
InChIKey
BGRWSFIQQPVEML-UHFFFAOYSA-N
XLogP
1.4
Polar surface area
56 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
353.028
Show 3 more facts
chemical formula
C₁₆H₁₂BrN₅
canonical SMILES
CC1=NN=C2N1C3=C(C=C(C=C3)Br)C(=NC2)C4=CC=CC=N4
Commons category
Pyrazolam
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections
Contents
  • Legal status
  • United Kingdom
  • United States
  • Synthesis
  • See also
  • References

Pyrazolam (SH-I-04) is a benzodiazepine derivative originally developed by a team led by Leo Sternbach at Hoffman-La Roche in the 1970s. It has since been "rediscovered" and sold as a designer drug since 2012.

Pyrazolam has structural similarities to alprazolam and bromazolam. Unlike other benzodiazepines, pyrazolam does not appear to undergo metabolism, instead being excreted unchanged in the urine.

Excerpted from Wikipedia’s “pyrazolam” article, available under the CC BY-SA 4.0 licence.

Gallery (2)