Structure via PubChem · Public domain (PubChem)
HU-210
Sign in to saveHU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 has a binding affinity of 0.061 nM at CB1 receptors compared to 40.7 nM for Δ9-THC. The binding pose of HU-210 to the CB1 receptor is similar to other synthetic cannabinoids.
Chemical data
- Formula
- C25H38O3
- Molecular weight
- 386.6 g/mol
- IUPAC name
- (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
- SMILES
- CCCCCCC(C)(C)C1=CC(=C2[C@@H]3CC(=CC[C@H]3C(OC2=C1)(C)C)CO)O
- InChIKey
- SSQJFGMEZBFMNV-WOJBJXKFSA-N
- XLogP
- 6.4
- Polar surface area
- 49.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Has part
- carbon
- Mass
- 386.282095
Show 5 more facts
- chemical formula
- C₂₅H₃₈O₃
- isomeric SMILES
- CCCCCCC(C)(C)C1=CC2=C([C@@H]3CC(=CC[C@H]3C(O2)(C)C)CO)C(=C1)O
- canonical SMILES
- CCCCCCC(C)(C)C1=CC2=C(C3CC(=CCC3C(O2)(C)C)CO)C(=C1)O
- Commons category
- HU-210
- stereoisomer of
- dexanabinol
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
11 sectionsContents
- Effects and research
- Chemistry
- Legal status
- New Zealand
- United States
- Alabama
- Florida
- Vermont
- See also
- References
- Further reading
HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 has a binding affinity of 0.061 nM at CB1 receptors compared to 40.7 nM for Δ9-THC. The binding pose of HU-210 to the CB1 receptor is similar to other synthetic cannabinoids.
==Effects and research==
Excerpted from Wikipedia’s “HU-210” article, available under the CC BY-SA 4.0 licence.