RASSF8
Sign in to saveAlso known as C12orf2, HOJ1, Ras association domain family member 8
Ras association domain-containing protein 8 is a protein that in humans is encoded by the RASSF8 gene.
Gene data
RASSF8- Name
- Ras association domain family member 8
- Type
- protein-coding
- Aliases
- C12orf2, HOJ1
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
via MyGene.info
Gene · Ensembl
Ras association domain family member 8
- Symbol
- RASSF8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:25,958,068-26,079,892
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RASSF8 PDB 2cs4.png
Show 7 more facts
- HomoloGene ID
- 5219
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/11228
- genomic end
- 26232825
- genomic start
- 26111962
- chromosome
- human chromosome 12
- cytogenetic location
- 12p12.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Ras association domain-containing protein 8 is a protein that in humans is encoded by the RASSF8 gene.
==References==
Excerpted from Wikipedia’s “RASSF8” article, available under the CC BY-SA 4.0 licence.