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raxibacumab

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Also known as Abthrax

Raxibacumab is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax. Its efficacy has been proven in rabbits and monkeys. In December 2012 raxibacumab was approved in the United States for the treatment of inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs, and for prophylaxis of inhalational anthrax when alternative therapies are not available or are not appropriate.

Wikidata facts

Has use
medication
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World Health Organisation international non-proprietary name
raxibacumab
has characteristic
biopharmaceutical
subject has role
monoclonal antibody
legal status (medicine)
boxed warning
Sources (2)

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Encyclopedic overview

4 sections
Contents
  • Side effects
  • Pharmacology
  • Development history
  • References

Raxibacumab is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax. Its efficacy has been proven in rabbits and monkeys. In December 2012 raxibacumab was approved in the United States for the treatment of inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs, and for prophylaxis of inhalational anthrax when alternative therapies are not available or are not appropriate.

The antibody was discovered in a joint venture between Cambridge Antibody Technology and Human Genome Sciences. Cambridge Antibody Technology discovered the antibody to Human Genome Sciences's target and, in 2012, HGS was purchased by GlaxoSmithKline (GSK). In 2017, CAT was acquired by Emergent BioSolutions

Excerpted from Wikipedia’s “raxibacumab” article, available under the CC BY-SA 4.0 licence.