RBM28
Sign in to saveAlso known as ANES, RNA binding motif protein 28
RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene. It is a nucleolar component of the spliceosomal ribonucleoprotein complexes.
Gene data
RBM28- Name
- RNA binding motif protein 28
- Type
- protein-coding
- Position
- 128,278,493–128,343,971 (−)
- Aliases
- ANES, NOP4
- Ensembl
- ENSG00000106344
- RefSeq RNA
- NM_001166135.2, NM_018077.3, NM_175880.2, NR_046216.1
- RefSeq protein
- NP_001159607.1, NP_060547.2
The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RNA binding motif protein 28
- Symbol
- RBM28
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:128,278,493-128,343,971
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene. It is a nucleolar component of the spliceosomal ribonucleoprotein complexes.
==References==
Excerpted from Wikipedia’s “RBM28” article, available under the CC BY-SA 4.0 licence.