retinoschisis
Sign in to saveAlso known as Retinoschisis (disorder), Retinoschisis unspecified (disorder), Retinoschisis, unspecified
Retinoschisis is an eye disease characterized by the abnormal splitting of the retina's neurosensory layers, usually in the outer plexiform layer. Retinoschisis can be divided into degenerative forms which are very common and almost exclusively involve the peripheral retina and hereditary forms which are rare and involve the central retina and sometimes the peripheral retina. The degenerative forms are asymptomatic and involve the peripheral retina only and do not affect the visual acuity. Some rarer forms result in a loss of vision in the corresponding visual field.
Key facts
- Medical condition (new).name
- Retinoschisis
- Medical condition (new).image
- X-linked recessive (2).svg
- Medical condition (new).caption
- This condition is usually inherited in an X-linked recessive manner.
- Medical condition (new).image_size
- 350px
- Medical condition (new).field
- Ophthalmology
via Wikipedia infobox
Research
2,148 papers- X-Linked Retinoschisis.Cold Spring Harbor perspectives in medicine · 2023
- Retinoschisis: splitting hairs on retinal splitting.Clinical & experimental optometry · 2020
- X-Linked Juvenile Retinoschisis.Advances in experimental medicine and biology · 2025
- [Papillomacular retinoschisis associated with glaucoma].Vestnik oftalmologii · 2019
- X-linked Juvenile Retinoschisis.Advances in experimental medicine and biology · 2018
via PubMed
Wikidata facts
- Subclass of
- disease
Show 6 more facts
- NCI Thesaurus ID
- C85046
- health specialty
- ophthalmology
- exact match
- purl.obolibrary.org/obo/HP_0030502
- anatomical location
- retina
- ICD-9-CM
- 361.10
- on focus list of Wikimedia project
- WikiProject Medicine
via Wikidata · CC0
~7 min read
Encyclopedic overview
11 sectionsContents
- Classification
- Degenerative retinoschisis
- Hereditary retinoschisis
- Tractional retinoschisis
- Exudative retinoschisis
- Diagnosis
- Treatment
- Gene therapy
- Gene editing
- References
- External links
Retinoschisis is an eye disease characterized by the abnormal splitting of the retina's neurosensory layers, usually in the outer plexiform layer. Retinoschisis can be divided into degenerative forms which are very common and almost exclusively involve the peripheral retina and hereditary forms which are rare and involve the central retina and sometimes the peripheral retina. The degenerative forms are asymptomatic and involve the peripheral retina only and do not affect the visual acuity. Some rarer forms result in a loss of vision in the corresponding visual field.
Almost all cases are X-linked recessive and caused by a mutation in the retinoschisin gene (RS1).
Excerpted from Wikipedia’s “retinoschisis” article, available under the CC BY-SA 4.0 licence.