RGPD5
Sign in to saveAlso known as BS-63, BS63, HEL161, RGP5, RANBP2-like and GRIP domain containing 5, RANBP2 like and GRIP domain containing 5
RANBP2-like and GRIP domain-containing protein 5 is a protein that in humans is encoded by the RGPD5 gene.
Gene data
RGPD5- Name
- RANBP2 like and GRIP domain containing 5
- Type
- protein-coding
- Position
- 109,792,758–109,857,705 (+)
- Aliases
- BS-63, BS63, HEL161, RGP5
- Ensembl
- ENSG00000015568
- RefSeq RNA
- NM_005054.3, NM_032260.3, XM_006712794.5, XM_017005081.3, XM_047445980.1
- RefSeq protein
- NP_005045.2, NP_115636.1, XP_006712857.2, XP_016860570.1, XP_047301936.1
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
RANBP2 like and GRIP domain containing 5
- Symbol
- RGPD5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:109,792,758-109,857,705
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RGPD5 PDB 1xke.png
Show 7 more facts
- HomoloGene ID
- 87808
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/84220
- chromosome
- human chromosome 2
- genomic start
- 113127669
- genomic end
- 109857705
- cytogenetic location
- 2q13
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
RANBP2-like and GRIP domain-containing protein 5 is a protein that in humans is encoded by the RGPD5 gene.
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined.
Excerpted from Wikipedia’s “RGPD5” article, available under the CC BY-SA 4.0 licence.