RHOJ

Also known as ARHJ, RASL7B, TC10B, TCL, ras homolog family member J

Rho-related GTP-binding protein RhoJ is a protein that in humans is encoded by the RHOJ gene.

Gene data

RHOJ

Name: ras homolog family member J
Type: protein-coding
Position: 63,204,114–63,293,518 (+)
Aliases: ARHJ, RASL7B, TC10B, TCL
Ensembl: ENSG00000126785
RefSeq RNA: NM_020663.5, XM_011536993.4, XM_047431613.1, XM_054376445.1, XM_054376446.1
RefSeq protein: NP_065714.1, XP_011535295.1, XP_047287569.1, XP_054232420.1, XP_054232421.1

This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011].

Pathways

Salmonella infection - Homo sapiens (human)Signal Transduction Signaling by Rho GTPases RHO GTPase cycle RHOJ GTPase cycle Signaling by Rho GTPases, Miro GTPases and RHOBTB3 VEGFA-VEGFR2 Signaling Pathway Insulin Signaling

via MyGene.info

Gene · Ensembl

ras homolog family member J

Symbol: RHOJ
Biotype: Protein coding
Organism: Homo sapiens
Location: 14:63,204,114-63,293,518
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

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Encyclopedic overview

2 sections

Contents

References
Further reading

Rho-related GTP-binding protein RhoJ is a protein that in humans is encoded by the RHOJ gene.

ARHJ belongs to the Rho family of small GTP-binding proteins. Rho proteins regulate the dynamic assembly of cytoskeletal components for several physiologic processes, such as cell proliferation and motility and the establishment of cell polarity. They are also involved in pathophysiologic process, such as cell transformation and metastasis.[supplied by OMIM]

Excerpted from Wikipedia’s “RHOJ” article, available under the CC BY-SA 4.0 licence.