Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C8H5F3N2OS
- Molecular weight
- 234.2 g/mol
- IUPAC name
- 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
- SMILES
- C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
- InChIKey
- FTALBRSUTCGOEG-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 76.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
2,265 papers- Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).The Cochrane database of systematic reviews · 2012
- The pharmacology and mechanism of action of riluzole.Neurology · 1996
- Riluzole for the treatment of amyotrophic lateral sclerosis.Neurodegenerative disease management · 2020
- A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group.The New England journal of medicine · 1994
- Riluzole.Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases · 2000
via PubMed
Wikidata facts
- Mass
- 234.007468
- Has use
- medication
Show 5 more facts
- chemical formula
- C₈H₅F₃N₂OS
- medical condition treated
- ALS
- canonical SMILES
- C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
- defined daily dose
- 0.1
- Commons category
- Riluzole
Sources (8)
via Wikidata · CC0
Article · Deutsch
Riluzol (Handelsname Rilutek®) ist ein Arzneistoff, der zur Behandlung der amyotrophen Lateralsklerose (ALS) angewandt wird. Er verlängert bei dieser Krankheit die Überlebensdauer der Patienten. Die chemische Substanz gehört zur Gruppe der Benzothiazole.
Abstract from DBpedia / Wikipedia · CC BY-SA