Structure via PubChem · Public domain (PubChem)
terodiline
Sign in to saveTerodiline is a drug used in urology as an antispasmodic.
Chemical data
- Formula
- C20H27N
- Molecular weight
- 281.4 g/mol
- IUPAC name
- N-tert-butyl-4,4-diphenylbutan-2-amine
- SMILES
- CC(CC(C1=CC=CC=C1)C2=CC=CC=C2)NC(C)(C)C
- InChIKey
- UISARWKNNNHPGI-UHFFFAOYSA-N
- XLogP
- 5
- Polar surface area
- 12 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1986
- Indications
- Urinary incontinence, Polyuria
via ChEMBL · EBI
Research
184 papers- Terodiline. A review of its pharmacological properties, and therapeutic use in the treatment of urinary incontinence.Drugs · 1990
- Terodiline in the treatment of diurnal enuresis in children.Scandinavian journal of primary health care · 1988
- Stereoselective cardiotoxic effects of terodiline.Clinical pharmacology and therapeutics · 1996
- [Terodiline (Mictrol)].Ugeskrift for laeger · 1987
- Actions of terodiline, its isomers and main metabolite on isolated detrusor muscle from rabbit and man.Pharmacology & toxicology · 1988
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 281.214
Show 4 more facts
- chemical formula
- C₂₀H₂₇N
- canonical SMILES
- CC(CC(C1=CC=CC=C1)C2=CC=CC=C2)NC(C)(C)C
- subject has role
- parasympatholytic
- defined daily dose
- 50
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Terodiline is a drug used in urology as an antispasmodic.
It relaxes the smooth muscle and used to reduce bladder tone in treatment of urinary frequency and incontinence. Muscle relaxation caused by terodiline, is probably due to its anticholinergic and calcium antagonist activity.
Excerpted from Wikipedia’s “terodiline” article, available under the CC BY-SA 4.0 licence.