RLIM
Sign in to saveAlso known as NY-REN-43, RNF12, ring finger protein, LIM domain interacting, MRX61, TOKAS
E3 ubiquitin-protein ligase RLIM is an enzyme that in humans is encoded by the RLIM gene.
Gene data
RLIM- Name
- ring finger protein, LIM domain interacting
- Type
- protein-coding
- Chromosome
- X
- Position
- 74,582,976–74,614,646 (−)
- Aliases
- MRX61, NY-REN-43, RNF12, TOKAS
- Ensembl
- ENSG00000131263
- RefSeq RNA
- NM_016120.4, NM_183353.3
- RefSeq protein
- NP_057204.2, NP_899196.1
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ring finger protein, LIM domain interacting
- Symbol
- RLIM
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:74,582,976-74,614,646
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7920
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51132
- chromosome
- human X chromosome
- genomic start
- 74582976
- genomic end
- 74614624
- cytogenetic location
- Xq13.2
- expressed in
- pars compacta
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
E3 ubiquitin-protein ligase RLIM is an enzyme that in humans is encoded by the RLIM gene.
== Function ==
Excerpted from Wikipedia’s “RLIM” article, available under the CC BY-SA 4.0 licence.