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safrazine

Structure via PubChem · Public domain (PubChem)

EntityQ7398833· pop 7· linked from 476 articles

Also known as Safra

Safrazine (Safra) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was introduced as an antidepressant in the 1960s, but has since been discontinued alongside several old generation MAOIs in favor of the invention of RIMAs and more efficacious treatments for depression in general.

Chemical data

Formula
C11H16N2O2
Molecular weight
208.26 g/mol
IUPAC name
1-(1,3-benzodioxol-5-ylmethyl)-2-propan-2-ylhydrazine
SMILES
CC(C)NNCC1=CC2=C(C=C1)OCO2
InChIKey
LHXBSYGNYYTTRM-UHFFFAOYSA-N
XLogP
1.9
Polar surface area
42.5 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Wikidata facts

Mass
208.121178
Has use
medication
Show 2 more facts
chemical formula
C₁₁H₁₆N₂O₂
canonical SMILES
CC(C)NNCC1=CC2=C(C=C1)OCO2
Sources (1)

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Safrazine (Safra) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was introduced as an antidepressant in the 1960s, but has since been discontinued alongside several old generation MAOIs in favor of the invention of RIMAs and more efficacious treatments for depression in general.

== See also == Hydrazine (antidepressant)

Excerpted from Wikipedia’s “safrazine” article, available under the CC BY-SA 4.0 licence.

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