sarolaner
Sign in to saveSarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. It is also used off-label to control sarcoptic mange and demodectic mange.
Research
142 papers- Sarolaner-a novel isoxazoline-addresses the need for enhanced flea and tick control.Veterinary parasitology · 2016
- Tradition and innovation: Selamectin plus sarolaner. A new tool to control endo- and ectoparasites of cats-Studies from North America and Japan.Veterinary parasitology · 2019
- Efficacy and safety of sarolaner (Simparica(®)) in the treatment and control of naturally occurring flea infestations in dogs presented as veterinary patients in Australia.Parasites & vectors · 2017
- Sarolaner/selamectin spot-on: An effective treatment of generalized demodicosis due to Demodex cati in a cat.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
- Safety of Simparica Trio(®) (sarolaner, pyrantel, moxidectin) in heartworm-infected dogs.Parasites & vectors · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 580.025
Show 4 more facts
- canonical SMILES
- CS(=O)(=O)CC(=O)N1CC2(C1)C3=C(CO2)C=C(C=C3)C4=NOC(C4)(C5=CC(=C(C(=C5)Cl)F)Cl)C(F)(F)F
- chemical formula
- C₂₃H₁₈Cl₂F₄N₂O₅S
- isomeric SMILES
- CS(=O)(=O)CC(=O)N1CC2(C1)C3=C(CO2)C=C(C=C3)C4=NO[C@@](C4)(C5=CC(=C(C(=C5)Cl)F)Cl)C(F)(F)F
- Commons category
- Sarolaner
Sources (1)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. It is also used off-label to control sarcoptic mange and demodectic mange.
Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel. It is used for prevention of heartworm disease caused by Dirofilaria immitis; treat and prevent flea infestations; treat and control tick infestations with the lone star tick, Gulf Coast tick, American dog tick, black-legged tick, and brown dog tick; and treat and control roundworm and adult hookworm infections.
Excerpted from Wikipedia’s “sarolaner” article, available under the CC BY-SA 4.0 licence.