Structure via PubChem · Public domain (PubChem)
sb-216641
Sign in to saveAlso known as SB-216,641
SB-216641 is a drug which is a selective antagonist for the serotonin receptor 5-HT1B, with around 25x selectivity over the closely related 5-HT1D receptor. It is used in scientific research, and has demonstrated anxiolytic effects in animal studies.
Chemical data
- Formula
- C28H30N4O4
- Molecular weight
- 486.6 g/mol
- IUPAC name
- N-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
- SMILES
- CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)OCCN(C)C
- InChIKey
- JRNUKVFYILMMLX-UHFFFAOYSA-N
- XLogP
- 5
- Polar surface area
- 89.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 486.226705
Show 2 more facts
- chemical formula
- C₂₈H₃₀N₄O₄
- canonical SMILES
- CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)OCCN(C)C
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
SB-216641 is a drug which is a selective antagonist for the serotonin receptor 5-HT1B, with around 25x selectivity over the closely related 5-HT1D receptor. It is used in scientific research, and has demonstrated anxiolytic effects in animal studies.
== See also == AR-A000002 GR-55562 GR-127935 SB-236057
Excerpted from Wikipedia’s “sb-216641” article, available under the CC BY-SA 4.0 licence.