SFRP4
Sign in to saveAlso known as FRP-4, FRPHE, sFRP-4, secreted frizzled related protein 4, PYL, FRZB-2
Secreted frizzled-related protein 4 is a protein that in humans is encoded by the SFRP4 gene.
Gene data
SFRP4- Name
- secreted frizzled related protein 4
- Type
- protein-coding
- Position
- 37,903,004–38,025,695 (−)
- Aliases
- FRP-4, FRPHE, FRZB-2, PYL, sFRP-4
- Ensembl
- ENSG00000106483
- RefSeq RNA
- NM_003014.4
- RefSeq protein
- NP_003005.2
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
secreted frizzled related protein 4
- Symbol
- SFRP4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:37,903,004-38,025,695
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~2 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Secreted frizzled-related protein 4 is a protein that in humans is encoded by the SFRP4 gene.
== Function ==
Excerpted from Wikipedia’s “SFRP4” article, available under the CC BY-SA 4.0 licence.