SFRP5
Sign in to saveAlso known as SARP3, secreted frizzled related protein 5
Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene.
Gene data
SFRP5- Name
- secreted frizzled related protein 5
- Type
- protein-coding
- Position
- 97,766,751–97,772,287 (−)
- Aliases
- SARP3
- Ensembl
- ENSG00000120057
- RefSeq RNA
- NM_003015.3
- RefSeq protein
- NP_003006.2
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
secreted frizzled related protein 5
- Symbol
- SFRP5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:97,766,751-97,772,287
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene.
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
Excerpted from Wikipedia’s “SFRP5” article, available under the CC BY-SA 4.0 licence.