SLC17A8
Sign in to saveAlso known as DFNA25, VGLUT3, solute carrier family 17 member 8
protein-coding gene in the species Homo sapiens
Gene data
SLC17A8- Name
- solute carrier family 17 member 8
- Type
- protein-coding
- Position
- 100,356,842–100,422,055 (+)
- Aliases
- DFNA25, VGLUT3
- Ensembl
- ENSG00000179520
- RefSeq RNA
- NM_001145288.2, NM_139319.3
- RefSeq protein
- NP_001138760.1, NP_647480.1
This gene encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. Mutations in this gene are the cause of autosomal-dominant nonsyndromic type 25 deafness. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
Gene Ontology
Biological process
Molecular function
Pathways
Synaptic vesicle cycle - Homo sapiens (human)Retrograde endocannabinoid signaling - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Nicotine addiction - Homo sapiens (human)DiseaseTransport of small moleculesSLC-mediated transmembrane transportSLC-mediated transport of neurotransmittersDefective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)SLC transporter disorders
via MyGene.info
Gene · Ensembl
solute carrier family 17 member 8
- Symbol
- SLC17A8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:100,356,842-100,422,055
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI