SLC1A1

Name

solute carrier family 1 member 1

Type

protein-coding

Position

4,490,207–4,587,469 (+)

Aliases

DCBXA, EAAC1, EAAT3, SCZD18, hEAAC1

Ensembl

ENSG00000106688

RefSeq RNA

NM_004170.6, XM_011518007.2, XM_011518008.4, XM_011518009.4, XM_011518010.2

RefSeq protein

NP_004161.4, XP_011516309.1, XP_011516310.1, XP_011516311.1, XP_011516312.1

This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010].

via MyGene.info

Gene · Ensembl

solute carrier family 1 member 1

Symbol

SLC1A1

Biotype

Protein coding

Organism

Homo sapiens

Location

9:4,490,207-4,587,469

Strand

Forward (+)

Assembly

GRCh38