Gene data
SLMAP- Name
- sarcolemma associated protein
- Type
- protein-coding
- Position
- 57,755,450–57,931,461 (+)
- Aliases
- SLAP
- Ensembl
- ENSG00000163681
- RefSeq RNA
- NM_001304420.3, NM_001304421.2, NM_001304422.3, NM_001304423.3, NM_001311178.2
- RefSeq protein
- NP_001291349.1, NP_001291350.1, NP_001291351.1, NP_001291352.1, NP_001298107.1
This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015].
Gene Ontology
Biological process
muscle contractionnegative regulation of hippo signalingnegative regulation of hippo signalingprotein localization to plasma membraneregulation of membrane depolarization during cardiac muscle cell action potentialregulation of membrane depolarization during cardiac muscle cell action potentialregulation of sodium ion transmembrane transport
Molecular function
via MyGene.info
Gene · Ensembl
sarcolemma associated protein
- Symbol
- SLMAP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:57,755,450-57,931,461
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 31428
- genetic association
- obesity
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7871
- genomic end
- 57930003
- genomic start
- 57741177
- chromosome
- human chromosome 3
- cytogenetic location
- 3p14.3
via Wikidata · CC0