Also known as sarcolipin
Sarcolipin is a micropeptide protein that in humans is encoded by the SLN gene.
Gene data
SLN- Name
- sarcolipin
- Type
- protein-coding
Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
sarcolipin
- Symbol
- SLN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:107,706,978-107,719,703
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein SLN PDB 1jdm.png
Show 4 more facts
- exact match
- identifiers.org/ncbigene/6588
- genomic end
- 107590419
- genomic start
- 107578104
- cytogenetic location
- 11q22.3
Sources (3)
via Wikidata · CC0
~2 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Sarcolipin is a micropeptide protein that in humans is encoded by the SLN gene.
== Function == Sarcoplasmic reticulum Ca2+-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca2+ from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. The SLN gene encodes a small transmembrane proteolipid that regulates several sarcoplasmic reticulum Ca2+-ATPases by reducing the accumulation of Ca2+ in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis.