SSX2IP
Sign in to saveAlso known as ADIP, synovial sarcoma, X breakpoint 2 interacting protein, SSX family member 2 interacting protein, hMsd1
Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene. It has been shown that it functions together with WDR8 in centrosome maturation, ensuring proper spindle length and orientation. The SSX2IP-WDR8 complex additionally promotes ciliary vesicle docking during ciliogenesis.
Gene data
SSX2IP- Name
- SSX family member 2 interacting protein
- Type
- protein-coding
- Position
- 84,643,121–84,690,955 (−)
- Aliases
- ADIP, hMsd1
- Ensembl
- ENSG00000117155
- RefSeq RNA
- NM_001166293.2, NM_001166294.2, NM_001166295.2, NM_001166417.2, NM_014021.4
- RefSeq protein
- NP_001159765.1, NP_001159766.1, NP_001159767.1, NP_001159889.1, NP_054740.3
This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
SSX family member 2 interacting protein
- Symbol
- SSX2IP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:84,643,121-84,690,955
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene. It has been shown that it functions together with WDR8 in centrosome maturation, ensuring proper spindle length and orientation. The SSX2IP-WDR8 complex additionally promotes ciliary vesicle docking during ciliogenesis.
== Interactions ==
Excerpted from Wikipedia’s “SSX2IP” article, available under the CC BY-SA 4.0 licence.