STAM2
Sign in to saveAlso known as Hbp, STAM2A, STAM2B, signal transducing adaptor molecule 2
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene.
Gene data
STAM2- Name
- signal transducing adaptor molecule 2
- Type
- protein-coding
- Aliases
- Hbp, STAM2A, STAM2B
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
signal transducing adaptor molecule 2
- Symbol
- STAM2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:152,116,801-152,175,781
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein STAM2 PDB 1x2q.png
Show 5 more facts
- HomoloGene ID
- 68490
- exact match
- identifiers.org/ncbigene/10254
- genomic end
- 152175763
- genomic start
- 152973315
- cytogenetic location
- 2q23.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene.
== Function ==