STAU1

Name

staufen double-stranded RNA binding protein 1

Type

protein-coding

Position

49,113,324–49,188,417 (−)

Aliases

PPP1R150, STAU

Ensembl

ENSG00000124214

RefSeq RNA

NM_001037328.3, NM_001319134.2, NM_001319135.2, NM_001322927.2, NM_001322928.2

RefSeq protein

NP_001032405.1, NP_001306063.1, NP_001306064.1, NP_001309856.1, NP_001309857.1

Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020].

via MyGene.info

Gene · Ensembl

staufen double-stranded RNA binding protein 1

Symbol

STAU1

Biotype

Protein coding

Organism

Homo sapiens

Location

20:49,113,324-49,188,417

Strand

Reverse (−)

Assembly

GRCh38