Structure via PubChem · Public domain (PubChem)
sulazepam
Sign in to saveSulazepam is a benzodiazepine derivative. It is the thioamide derivative of diazepam. It is metabolised into diazepam, desmethyldiazepam and oxydiazepam. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic properties like those of other benzodiazepines. It was never marketed.
Chemical data
- Formula
- C16H13ClN2S
- Molecular weight
- 300.8 g/mol
- IUPAC name
- 7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepine-2-thione
- SMILES
- CN1C(=S)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
- InChIKey
- MWGWTOPCKLQYEU-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 47.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 300.049
Show 3 more facts
- chemical formula
- C₁₆H₁₃ClN₂S
- canonical SMILES
- CN1C(=S)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
- Commons category
- Sulazepam
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Sulazepam is a benzodiazepine derivative. It is the thioamide derivative of diazepam. It is metabolised into diazepam, desmethyldiazepam and oxydiazepam. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic properties like those of other benzodiazepines. It was never marketed.
==Synthesis== thumb|center|400px|Sulazepam synthesis: Treatment of diazepam with phosphorus pentasulfide produces the corresponding thionamide, sulazepam. == See also == Uldazepam
Excerpted from Wikipedia’s “sulazepam” article, available under the CC BY-SA 4.0 licence.
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