sulfite oxidase
Sign in to saveAlso known as SUOX, sulfite oxidase, mitochondrial, uniprot:P51687
mammalian protein found in Homo sapiens
In the Vinony graph
Within Vinony's link graph, sulfite oxidase is referenced by 88 other articles, and connects out to PubMed, PubMed Central and Gene Ontology.
It sits within the topics EC 1.8.3, Genes on human chromosome 12 and Metalloproteins.
Its subject is documented across 15 Wikipedia language editions.
Protein · UniProt
Sulfite oxidase, mitochondrial
- Gene
- SUOX
- Organism
- Homo sapiens (Human)
- Length
- 545 aa
- Molecular mass
- 60,283 Da
- Evidence
- 1: Evidence at protein level
Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids (By similarity). Can run in reverse direction and reduce nitrite to nitric oxide under physiologically relevant conditions, such as hypoxia (PubMed:41337830)
Swiss-Prot (reviewed) · via UniProt
Research
998 papersvia PubMed
Clinical Trials
4 registered- PHASE1COMPLETEDPhase 1 Single Dose Study of ALXN1101 in Healthy VolunteersOrigin Biosciences · NCT01894165
- PHASE2COMPLETEDSafety & Efficacy Study of ORGN001 (Formerly ALXN1101) in Pediatric Patients With MoCD Type A Currently Treated With rcPMPOrigin Biosciences · NCT02047461
- COMPLETEDA Natural History Study of Molybdenum Cofactor and Isolated Sulfite Oxidase DeficienciesOrigin Biosciences · NCT01735188
- PHASE2/PHASE3COMPLETEDStudy of ORGN001 (Formerly ALXN1101) in Neonates, Infants and Children With Molybdenum Cofactor Deficiency (MOCD) Type AOrigin Biosciences · NCT02629393
Wikidata facts
- Instance of
- protein
Show 4 more facts
- Commons category
- Sulfite oxidase
- cell component
- mitochondrion
- found in taxon
- Homo sapiens
- exact match
- purl.uniprot.org/uniprot/P51687
via Wikidata · CC0