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GeneQ18034862· pop 5· linked from 9 articles

Also known as HsT19680, synaptic vesicle glycoprotein 2B

Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.

Gene data

SV2B
Name
synaptic vesicle glycoprotein 2B
Type
protein-coding
Aliases
HsT19680, SLC22B2

This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016].

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Gene · Ensembl

synaptic vesicle glycoprotein 2B

Symbol
SV2B
Biotype
Protein coding
Organism
Homo sapiens
Location
15:91,099,700-91,302,565
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
32236
genomic end
91302565
genomic start
91643180
cytogenetic location
15q26.1
Sources (3)

via Wikidata · CC0

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  • Further reading

Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.

==See also== SV2A

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