SYNJ2
Sign in to saveAlso known as INPP5H, synaptojanin 2
Synaptojanin 2 is a protein that in humans is encoded by the SYNJ2 gene.
Gene data
SYNJ2- Name
- synaptojanin 2
- Type
- protein-coding
- Position
- 157,981,863–158,099,176 (+)
- Aliases
- INPP5H
- Ensembl
- ENSG00000078269
- RefSeq RNA
- NM_001178088.2, NM_001410947.1, NM_003898.4, XM_005267198.5, XM_005267200.2
- RefSeq protein
- NP_001171559.1, NP_001397876.1, NP_003889.1, XP_005267255.1, XP_005267257.1
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Gene Ontology
Biological process
Molecular function
nucleic acid bindingRNA bindingphosphatidylinositol-3-phosphate phosphatase activityphosphatidylinositol-3-phosphate phosphatase activityphosphatidylinositol-4,5-bisphosphate 5-phosphatase activityphosphatidylinositol-4,5-bisphosphate 5-phosphatase activityphosphatidylinositol-4,5-bisphosphate 5-phosphatase activityphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
Pathways
via MyGene.info
Gene · Ensembl
synaptojanin 2
- Symbol
- SYNJ2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:157,981,824-158,099,176
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 117703
- exact match
- identifiers.org/ncbigene/8871
- genomic end
- 158520208
- genomic start
- 157981863
- cytogenetic location
- 6q25.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Synaptojanin 2 is a protein that in humans is encoded by the SYNJ2 gene.
== Function ==
Connections
Q180686
Entity
human chromosome 6
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
Entity
gene
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chromosome
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public domain
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digital object identifier
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plasma membrane
Entity
bibcode
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human genome
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Q229883
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base pair
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locus
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gene expression
Entity
endocytosis
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Online Mendelian Inheritance in Man
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United States National Library of Medicine
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Protein Data Bank
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