talopram
Sign in to saveAlso known as Phthalapromine
Talopram (Lu 3-010), also known as phthalapromine, is a selective norepinephrine reuptake inhibitor (NRI) which was researched for the management of depression in the 1960s and 1970s but was never commercialized. Along with talsupram, talopram is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram, as well as to melitracen:
Wikidata facts
- Mass
- 295.193614
Show 3 more facts
- chemical formula
- C₂₀H₂₅NO
- canonical SMILES
- CC1(C2=CC=CC=C2C(O1)(CCCNC)C3=CC=CC=C3)C
- Commons category
- Talopram
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Article
3 sectionsContents
- Synthesis
- See also
- References
Talopram (Lu 3-010), also known as phthalapromine, is a selective norepinephrine reuptake inhibitor (NRI) which was researched for the management of depression in the 1960s and 1970s but was never commercialized. Along with talsupram, talopram is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram, as well as to melitracen:
==Synthesis== An unexpected/fortuitous rearrangement product in the synthesis of litracen is what led to talopram.