TCEA2

Name

transcription elongation factor A2

Type

protein-coding

Position

64,049,836–64,072,352 (+)

Aliases

TFIIS

Ensembl

ENSG00000171703

RefSeq RNA

NM_003195.6, NM_198723.2, XM_005260229.5, XM_024451976.2, XM_024451981.2

RefSeq protein

NP_003186.1, NP_942016.1, XP_005260286.1, XP_024307744.1, XP_024307749.1

The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].