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tebufenpyrad

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EntityQ285594· pop 7· linked from 206 articles

tebufenpyrad

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Also known as 1H-Pyrazole-5-carboxamide, 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-, 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide, N-(4-t-butylbenzyl)-4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide, Pyranica

Tebufenpyrad is an insecticide and acaricide widely used in greenhouses. It is a white solid chemical with a slight aromatic smell. It is soluble in water and also in organic solvents.

Chemical data

Formula
C18H24ClN3O
Molecular weight
333.9 g/mol
IUPAC name
N-[(4-tert-butylphenyl)methyl]-4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide
SMILES
CCC1=NN(C(=C1Cl)C(=O)NCC2=CC=C(C=C2)C(C)(C)C)C
InChIKey
ZZYSLNWGKKDOML-UHFFFAOYSA-N
XLogP
4.5
Polar surface area
46.9 Ų
H-bond donors
1
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
333.161
Show 3 more facts
chemical formula
C₁₈H₂₄ClN₃O
canonical SMILES
CCC1=NN(C(=C1Cl)C(=O)NCC2=CC=C(C=C2)C(C)(C)C)C
Commons category
Tebufenpyrad
Sources (2)

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~3 min read

Encyclopedic overview

6 sections
Contents
  • Mode of action
  • Use
  • Exposure and toxicity
  • Biotransformation
  • Consequences of exposure
  • References

Tebufenpyrad is an insecticide and acaricide widely used in greenhouses. It is a white solid chemical with a slight aromatic smell. It is soluble in water and also in organic solvents.

==Mode of action== Tebufenpyrad is a strong mitochondrial complex I inhibitor. It is one of the METI acaricides and insecticides in IRAC group 21A. Like rotenone, it inhibits electron transport chain by inhibiting the complex I enzymes of mitochondria which ultimately leads to lack of ATP production and finally cell death.

Excerpted from Wikipedia’s “tebufenpyrad” article, available under the CC BY-SA 4.0 licence.

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