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GeneQ18031980· pop 5· linked from 4 articles

THBS3

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Also known as TSP3, thrombospondin 3

protein-coding gene in the species Homo sapiens

Gene data

THBS3

Name: thrombospondin 3
Type: protein-coding
Position: 155,195,587–155,209,051 (−)
Aliases: TSP3
Ensembl: ENSG00000169231
RefSeq RNA: NM_001252607.2, NM_001252608.2, NM_001407487.1, NM_001407488.1, NM_001407490.1
RefSeq protein: NP_001239536.1, NP_001239537.1, NP_001394416.1, NP_001394417.1, NP_001394419.1

The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011].

Gene Ontology

Biological process

cell adhesion cell-matrix adhesion

Molecular function

extracellular matrix structural constituent calcium ion binding calcium ion binding protein binding heparin binding heparin binding

Cellular component

extracellular region extracellular region extracellular matrix extracellular matrix perinuclear region of cytoplasm thrombospondin complex

Pathways

Phagosome - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Focal adhesion - Homo sapiens (human)ECM-receptor interaction - Homo sapiens (human)Malaria - Homo sapiens (human)Human papillomavirus infection - Homo sapiens (human)Signal Transduction Signaling by PDGF Signaling by Receptor Tyrosine Kinases Focal Adhesion

via MyGene.info

Gene · Ensembl

thrombospondin 3

Symbol: THBS3
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:155,195,584-155,209,203
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 5159
exact match: identifiers.org/ncbigene/7059
genomic end: 155178842
genomic start: 155165379
cytogenetic location: 1q22

Sources (4)

via Wikidata · CC0

Available in 4 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 1 Thrombospondins