Structure via PubChem · Public domain (PubChem)
thiomersal
Sign in to saveAlso known as o-(ethylmercurithio)benzoic acid sodium salt, ethylmercurithiosalicylate sodium, mercurothiolate, sodium ethylmercurithiosalicylate, Thiomersalum, sodium merthiolate, thiomersalate, Thimerosal
Thiomersal (INN), or thimerosal (USAN, JAN), also sold under the name merthiolate, is an organomercury compound. It is a well-established antiseptic and antifungal agent.
Chemical data
- Formula
- C9H9HgNaO2S
- Molecular weight
- 404.82 g/mol
- SMILES
- C[CH2].C1=CC=C(C(=C1)C(=O)[O-])[S-].[Na+].[Hg+]
- InChIKey
- RTKIYNMVFMVABJ-UHFFFAOYSA-L
- Polar surface area
- 41.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
2,040 papers- Thiomersal-containing vaccines - a review of the current state of knowledge.Przeglad epidemiologiczny · 2015
- Thiomersal.Contact dermatitis · 1979
- Thiomersal in vaccines: is removal warranted?Drug safety · 2001
- Vaccines without thiomersal: why so necessary, why so long coming?Drugs · 2001
- [Thiomersal and immunisations].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2004
via PubMed
~10 min read
Encyclopedic overview
12 sectionsContents
- History
- Synthesis
- Structure
- Uses
- Antiseptic/antifungal
- Toxicology
- General toxicity
- As an allergen
- Removal from vaccines
- Disproven autism hypothesis
- See also
- References
Thiomersal (INN), or thimerosal (USAN, JAN), also sold under the name merthiolate, is an organomercury compound. It is a well-established antiseptic and antifungal agent.
It has been used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. Despite the scientific consensus that fears about its safety are unsubstantiated, its use as a vaccine preservative has been exploited by anti-vaccination groups.
Excerpted from Wikipedia’s “thiomersal” article, available under the CC BY-SA 4.0 licence.